My hi-tech Library

Chapter 271? The epitome of the times (2)

Chapter 271? The epitome of the times (2)

Xingyao Experimental Center, biological experimental area.

Professor Wei Zhihan led his scientific research team to conduct in-depth research on gene enhancement projects.

Jiang Ming is a researcher of one of the sub-projects of the Human Gene Enhancement Project. As usual, he drove a flying car into the experimental area and arrived at the laboratory after passing a series of security tests.

"Good morning! Mr. Chen, Sister Lin!" Jiang Ming changed into his lab coat and greeted his colleagues - Chen Kai and Lin Meifeng with a smile.

"Morning? Don't you look at the time! It's almost noon now." Lin Meifeng teased with a smile.

"That's right, Xiaolin and I have been busy all morning, but you are late, old rules, you will arrange the activities next week." Chen Kai looked at Jiang Ming and gestured.

"Brother Chen, I was busy until 2 a.m. last night. I didn't make any progress with the work I just did." Jiang Ming smiled and explained quickly.

"You're staying up late to work overtime again. Next time, I will file a complaint with Director Sun." Lin Meifeng glared at Jiang Ming and reminded him.

In order to prevent scientific researchers from working for a long time and ignoring their physical health, the experimental center has formulated reasonable work and rest regulations. However, there are still many scientific researchers who ignore these regulations, and the project is delved into a fascination. Staying up late to work overtime is common matter.

"Sister Lin, don't threaten me. I had to stay up late and work overtime because of special circumstances last night. This is in line with the regulations of our department." Jiang Ming explained with a smile.

"What special circumstances did you make a breakthrough in your research last night?" Chen Kai turned to look at Jiang Ming and asked with concern.

Lin Meifeng stopped what she was doing and looked at Jiang Ming.

Jiang Ming nodded with a smile, and turned on the virtual screen of the console: "Brother Chen, Sister Lin, come and see the results of my work last night! If nothing else, our group's scientific research work should be completed! "

Hearing this, Chen Kai and Lin Meifeng stepped forward one after another.

I saw that a three-dimensional image of an intestinal tube appeared on the virtual screen, and various data were marked around it. It was the experimental data result of the original intestinal tube of a mouse.

In mammalian embryonic development, the original gut is the precursor of many important organs, including the intestine, stomach, pancreas, liver, lung, esophagus, pharynx and thyroid. Therefore, the development and differentiation of the original gut has always been the focus of embryonic development research.

Unlike mesoderm cells that will develop into mesenchymal cells, endoderm cells, which exist as a single layer of cells within the gastrula duct, will form functional epithelial cells in various organs, such as absorptive cells in the intestine, acid-secreting cells in the stomach parietal cells of the pancreas, and exocrine cells of the pancreas. During the organogenesis stage of mouse gestational age 9.5-13.5 days, the intestinal canal gradually began to appear organ precursors with morphological characteristics.

This process is dominated by mesoderm cells, while the endoderm still maintains a monolayer cell morphology at this stage.

Jiang Ming and his group are mainly responsible for experimentally verifying the effects of abnormal expression of key enhancing gene factors on organ differentiation and cell lineage fate determination in mouse models.

The genetic enhancement project has been in progress for more than half a year, during which many scientific research results have been achieved, but there is still a long way to go before the completion of human genetic enhancement.

All biochemical experiments are located in the laboratory of the lunar base, and Jiang Ming and the others have achieved ultra-long-distance experimental connections through a virtual network.

Last night, Jiang Ming had a brainstorm and thought of a new idea, so he carried out a remote experiment according to his idea. The experimental results seemed to be the same endoderm cells showed different gene expression patterns along the anterior-posterior axis, even in the development of the intestinal tract. Some organ-specific genes are expressed at the earliest stage.

Soon, Chen Kai and Lin Meifeng both discovered the unusualness of the experimental data.

"You, how did you do it?" Chen Kai suddenly turned his head and asked Jiang Ming in surprise.

"I found that knocking out key transcription factors directly shifts cell lineages, for example, knocking out Sox2 shifts the chromatin epiome state of gastric epithelial cells to the chromatin state of adjacent organs such as the lung; The Cdx2 gene will change the chromatin state of intestinal epithelial cells to the chromatin state of the fore-gut (fut), ..., so I tried this direction." Jiang Ming explained with a smile,

After a pause, Jiang Ming continued: "So, I conducted an experiment on SOX2 and CDX2, two transcription factors that are crucial for the maturation and differentiation of intestinal epithelial cells, by comparing the chromatin after knockout of Sox2 or Cdx2. The changes in the state compared to the control group, combined with the unique chromatin accessibility patterns of different organs, ..., the result, hehe, I really found the key gene."

"Great! According to this experimental direction, our project has finally broken through." Lin Meifeng said with joy.

"Yeah! The experimental results confirm the activity of organ-specific gene transcriptional activity, based on high-throughput sequencing technology to measure chromatin accessibility at the genome-wide level, and can identify potential regulatory regions and transcriptional regions within the genome. Factor binding sites, ..., the cooperative participation of chromatin state and transcription factors in the regulation of gene expression during intestinal development, this set of experimental data is too precious." Chen Kai nodded excitedly, highly agreeing with Jiang Ming's experimental results .

"Have you reported the experimental results?" Lin Meifeng looked at Jiang Ming and asked with concern.

"Not yet! Last night was too late. I'm going to submit the results of this project today. Brother Chen, Sister Lin, can you do me a favor!" Jiang Ming smiled and looked at Chen Kai, and Lin Meifeng suggested.

Hearing this, Chen Kai and Lin Meifeng were all invigorated.

"Xiaojiang, this is the result of your experiment. It's inappropriate for us to participate now!" Chen Kai said embarrassedly.

"Yes! This research result is your discovery..." Lin Meifeng nodded in agreement.

"What is this? We did this project together. Without your hard work in the early stage of scientific research, how could I have made today's breakthrough? This scientific research project was made by us together, and the result is of course shared! Besides, our center is not There is a sharing system for scientific research results! Just follow the system process!" Jiang Ming explained with a smile.

Hearing this, Chen Kai and Lin Meifeng nodded happily, no longer struggling.

"Okay, let's do the finishing work, you can write the project completion form!" Chen Kai said decisively.

Jiang Ming nodded and started to get busy.

Soon, the three of them went into the finishing touches of the scientific research project together in high spirits.

In the Xingyao Experimental Center, there are hundreds of thousands of scientific research groups with Jiang Ming, Chen Kai, Lin Meifeng and the others. Even a single person can set up a scientific research project team to undertake the scientific research tasks of the experimental center.

According to the difficulty of scientific research tasks, members of the scientific research team, with the same major or different majors, gather the intelligence of the group to overcome those complex scientific research work together.

In just one genetic enhancement research project, there are hundreds of scientific research groups working together to carry out scientific research work on this large scientific research project.

Soon, Jiang Ming wrote the completion form of the scientific research project, and uploaded the report to the human genetic enhancement project team through the scientific research intelligent assistance system. project member.

Biological gene research area, large conference room.

Professor Wei Hanzhi and a group of scientific research members are conducting a scientific research meeting, discussing the scientific research results successfully conquered every day, and bringing together the research results of all scientific research groups to promote the scientific research progress of the entire scientific research project.

"Professor Wei, Professor Wei, look at the chromatin epigenetics project. The research of group 172 has made a breakthrough, and the research results on the potential expression of alienation genes have come out."

The seminar was in progress, and suddenly one of the participants exclaimed loudly, and his voice seemed particularly excited.

"Wow! The research results are out!"

"This breakthrough is too critical, Professor Wei, let's start the human cell experiment!"

"The research on the alienation performance of the key factors of the genetic code has been completed, and the risk of the experiment has been greatly reduced."

"Yeah! It's time for human gene fusion experiments."

...

After the researchers confirmed the news, they looked at Professor Wei Hanzhi excitedly and proposed to him.

"Okay! I'll confirm with President Li. If there is no problem, we will start the next experimental process." Professor Wei Hanzhi responded happily with a face full of joy.

After speaking, Professor Wei Hanzhi looked at Liu Chengfeng, who was sitting on his right, and instructed, "Old Liu, everyone has worked hard during this time, confirm the scientific research results as soon as possible, and arrange the scientific research bonus as soon as possible."

"Well! I'll make arrangements as soon as possible." Liu Chengfeng readily answered the order.

In the afternoon, after Professor Wei Hanzhi had a call with Li Yi, the entire gene enhancement project was pushed forward with great speed.

However, all this has nothing to do with Jiang Ming, Chen Kai, Lin Meifeng and the others. After submitting their scientific research results, their scientific research work has come to an end. After more than half a year, they finally have time to start vacation.

Jiang Ming drove the new flying car - Night Elf II, at a speed close to the speed of sound, galloping on the high-speed highway in the sky, and the magnificent city scenery of Xingyao City was unobstructed.

"Dongdong..." The car audio suddenly sounded a call to remind you.

"Wade, turn on the autopilot mode and answer the call." Jiang Ming gestured quickly.

"Okay, boss!" On the virtual screen in the car, the head of a little boy appeared, and the next moment, the steering wheel in the car shrank.

Immediately afterwards, a larger virtual screen appeared, and a full-body image of a girl with a round face appeared, which was his girlfriend, Zhang Yingying.

"Aren't you in the lab? Where are you!" Zhang Yingying asked as soon as the video call was connected.

"I'm going for a ride outside! The Shadow Prince who just started doesn't have time to drive it out to play. I plan to stroll around for a while, and I'll pick you up soon." Jiang Ming explained with a smile.

After a pause, Jiang Ming looked at his girlfriend and suggested: "The scientific research project is over, I have time to accompany you now, don't you want to travel around the world! Why don't you take this opportunity to realize this idea?"

Hearing this, Zhang Yingying was heartbroken, but when she thought that she still had work to do, she couldn't spare so much time, and she was immediately discouraged.

"What? Can't go?" Looking at his girlfriend's dejected expression, Jiang Ming asked unexpectedly.

"Yeah! I'm so busy with work, so I can take a long vacation!" Zhang Yingying sighed.

"Why don't you quit your job!" Jiang Ming suggested.

Zhang Yingying turned silver and said, "If you quit me, what will you eat and drink the northwest wind!"

"I quit my job, I will support you! There is a lot of funds left for this research project. With a considerable scientific research bonus, it should not be a problem to support you." Jiang Ming smiled and introduced confidently.

"Raise me? Are you proposing to me?" Zhang Yingying blinked and asked with a smile.

Jiang Ming was refreshed and confirmed with a smile: "Yes! Mrs. Jiang, let's take this global tour as our honeymoon, okay?"

"Proposed to me on the phone, Jiang Ming, you stupid wood, do you want to die!" Zhang Yingying's face changed and she asked angrily.

After speaking, Zhang Yingying hung up the video call angrily.

...

Jiang Ming was stunned for a moment, then remembered something, and immediately realized that he was overwhelmed.

"Wade, help me set a dining table at Dizhuang, and at the same time help me prepare a bouquet and a wedding finger. I want to propose to my girlfriend." Jiang Ming quickly took remedial measures and ordered ~ Boss, can you reserve a table at the viewing area? There is also a proposal ring, please choose a style." A sound of electronic synthesis sounded in the car.

Soon, the virtual screen changed, and there was a dining table in front of the large floor-to-ceiling windows overlooking the night view of the entire Xingyao City, as well as more than a dozen wedding rings ranging in price, which was convenient for Jiang Ming to choose.

"Well, the location is good, let's choose the fifth ring!" Jiang Ming decided on the choice of the dining table, and chose a beautiful and moderately priced wedding ring.

"Okay, boss, what are you going to have for dinner! Do you order according to Miss Zhang's preference?" Wade went on to remind.

"Okay, it depends on her appetite, and if you propose marriage, does Emperor Zhuang provide any services?" Jiang Ming quickly confirmed.

"Yes, they provide twelve atmosphere group services for marriage proposals." Wade responded readily, and the next moment, twelve additional service options appeared on the screen.

Jiang Ming carefully previewed it. The price points are different, and the content of the service is also different. There are professional dance performances, various atmosphere-enhancing links, playing videos, photos, ..., etc., very professional.

Unfortunately, it has been revealed in advance that there is no remedy now, otherwise, Yingying will definitely be moved to the point of not marrying him.

"Just this one! Is it too late to make arrangements for the evening?" Jiang Ming chose a nostalgic version and asked.

"Yes, boss, this one will provide the merchant with a video and photo of you and Miss Zhang." Wade indicated.

"Well! Select some meaningful and beautiful ones from my data space and send them to them!" Jiang Ming nodded and ordered.

"Okay, boss, it has been arranged. The total consumption is 327,000. If there is no problem, please enter the payment password." The intelligent assistant - Wade responded.

Jiang Ming nodded, operated on the virtual screen, and the payment was successful.